2007/07/23

Cell Cycle

Process
Because meiosis is a "one-way" process, it cannot be said to engage in a cell cycle as mitosis does. However, the preparatory steps that lead up to meiosis are identical in pattern and name to the interphase of the mitotic cell cycle.
Interphase is divided into three phases:






·Growth 1 (G1) phase: Immediately follows cytokenesis. This is a very active period, where cell synthesizes its vast array of proteins, including the enzymes and structural proteins it will need for growth. In G1 stage each of the 46 human chromosomes consists of a single (very long) molecule of DNA
·Synthesis (S) phase: The genetic material is replicated: each of its chromosomes duplicates. The cell is still diploid, however, because it still contains the same number of centromeres. However, the identical sister chromatids are in the chromatin form because spiralisation and condensation into denser chromosomes have not taken place yet. It will take place in prophase I in meiosis.
·Growth 2 (G2) phase: The cell continues to grow making the cell larger.
Interphase is immediately followed by meiosis I and meiosis II. Meiosis I consists of segregating the homologous chromosomes from each other, then dividing the diploid cell into two haploid cells each containing one of the segregates. Meiosis II consists of decoupling each chromosome's sister strands (chromatids), segregating the DNA into two sets of strands (each set containing one of each homolog), and dividing both haploid, duplicated cells to produce four haploid, unduplicated cells. Meiosis I and II are both divided into prophase, metaphase, anaphase, and telophase subphases, similar in purpose to their analogous subphases in the mitotic cell cycle. Therefore, meiosis encompasses the interphase (G1, S, G2), meiosis I (prophase I, metaphase I, anaphase I, telophase I), and meiosis II (prophase II, metaphase II, anaphase II, telophase II).

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